Small-Scale In-Line Mixers
Small-Scale In-Line Mixers
Silverson’s range of small-scale In-Line mixers is specifically designed to provide high performance and versatility for a variety of mixing applications. These mixers effectively bridge the gap between laboratory and full-scale production models, offering precision mixing for mid-range batch sizes.
As one of the most versatile mixers on the market, Silverson high shear rotor/stator In-Line mixers have the ability to form stable emulsions, de-agglomerate, reduce particle and droplet sizes and blend powdered and liquid ingredients. The rotor/stator workhead is impossible to bypass, so all material is subjected to high shear as it passes through the workhead. Before now these mixers have only been available as a production-scale model or as a benchtop laboratory unit. The new mixer range, which includes “Ultra Hygienic” specification models, a unit suitable for higher viscosity mixes, and a Multi-stage In-Line mixer, complement the different types of laboratory and production models already available from Silverson, but importantly offer customers more options in terms of batch sizes and processing requirements.
Any mixer in this range can be supplied with a Vessel Package, increasing the versatility and flexibility of these small-scale mixers. The Vessel package comprises of a 50 liter vessel, vessel stand, valve and pipework. Conversion kits are also available allowing the UHS model to be upgraded to a UHS-HV and an FMX10.
Small-Scale In-Line Mixer Range:
How It Works
Our small-scale In-Line mixers provide processors with numerous advantages, including high speed, versatility, self-pumping, aeration-free operation, and guaranteed efficiency. Featuring Silverson’s precision-engineered rotor/stator workhead, these compact mixers provide the same exceptional mixing quality as larger models even for smaller batches.
The high-speed rotation of the rotor blades within the precision-machined mixing workhead exerts a powerful suction, drawing liquid and solid materials into the rotor/stator assembly.
Centrifugal force then drives the materials towards the periphery of the workhead where they are subjected to a milling action in the precision-machined clearance between the ends of the rotor blades and the inner wall of the stator.
This is followed by intense hydraulic shear as the materials are forced, at high velocity, out through the perforations in the stator, then through the machine outlet and along the pipework. At the same time, fresh materials are continually drawn into the workhead, maintaining the mixing and pumping cycle.
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Stage 1
Stage 1
The high-speed rotation of the rotor blades within the precision-machined mixing workhead exerts a powerful suction, drawing liquid and solid materials into the rotor/stator assembly.
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Stage 2
Stage 2
Centrifugal force then drives the materials towards the periphery of the workhead where they are subjected to a milling action in the precision-machined clearance between the ends of the rotor blades and the inner wall of the stator.
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Stage 3
Stage 3
This is followed by intense hydraulic shear as the materials are forced, at high velocity, out through the perforations in the stator, then through the machine outlet and along the pipework. At the same time, fresh materials are continually drawn into the workhead, maintaining the mixing and pumping cycle.
Videos
150 UHS Small-Scale Ultra Sanitary In‑Line Mixer
UHS-HV Small-Scale High Viscosity In‑Line Mixer
088/150 UHS Small-Scale Multistage In‑Line Mixer
Mixer Options
150 UHS Small-Scale Ultra Sanitary In-Line Mixer
The 150 UHS In-Line is designed for Ultra Sanitary applications typically encountered in the pharmaceutical and biotech industries, where the smallest production scale mixers may be too large, but laboratory equipment may not offer sufficient capacity. This model is built to the same high specification as production-scale UHS mixers and can be supplied with Silverson-designed hygienic single mechanical shaft seals, which can be converted to hygienic double mechanical shaft seals suitable for pressurised flush. They have a crevice-free construction and are designed for Clean-In-Place (CIP) and Sterilize-In-Place (SIP) operations. Ideal for batches of up to 50 liters, the mixer features a range of interchangeable workheads and screens, offering intense yet targeted high shear capability; a conversion kit allowing it to be used as a Multistage 088/150 is available. The mixer can be supplied with data dossier documentation packages conforming to all regulatory standards, for example, cGMP and FDA and EC1935/2004.
UHS-HV Small-Scale High Viscosity In-Line Mixer
The UHS-HV is the go-to solution for small-scale in-line manufacturing of higher viscosity products, matching the capabilities of production-scale Silverson HV In-Line mixers. It features a unique “pumping rotor” design that significantly increases self-pumping capacity, maintaining high flow rates of around 6,500 liters/hour even as viscosity rises. This innovative design often eliminates the need for an additional feed pump when processing higher viscosity products like creams, ointments, sauces, and slurries. With multiple motor options available, including high-speed variants up to 9,000 rpm for continuous recirculation of viscous products, as well as stainless steel and Flameproof models, this mixer offers exceptional versatility for a wide range of applications.
088/150 Small-Scale Multistage In-Line Mixer
As Silverson’s first small-scale Multistage In-Line mixer, the 088/150 revolutionizes small-batch processing by bringing production-scale efficiency to smaller operations. It increases the number of shearing actions per revolution, resulting in substantially faster mixing times and expanded processing capabilities. The Multistage workhead allows for customizable configurations to meet individual requirements; for example, the inner stator can be set as a General Purpose Disintegrating Head, while the outer stator could be a Slotted Disintegrating Head. This versatility enables quick optimization for specific applications, increasing the number of products that can be processed in a single pass. The 088/150 is an efficient choice for manufacturers looking to streamline their mixing operations, offering enhanced mixing versatility and performance in a compact design.
FMX10 Small-Scale Powder/Liquid Mixer
The FMX10 was designed to bridge the gap between laboratory and production-scale Flashmix ranges, offering a perfect middle ground for many operations. It provides a simple, effective, and sanitary means of powder/liquid mixing for batches up to 50 liters, depending on viscosity. Featuring the same pumping rotor design as the HV model, the FMX10 excels at processing higher viscosity mixes. With options for high-speed motors and Flameproof specifications, this mixer delivers exceptional versatility for diverse mixing needs. The standard powder feed hopper has a 5 liter capacity. Different designs are available to assist with the flow of more cohesive powders.
Vessel Package
All small-scale mixers can be supplied with a Vessel package comprising a 50 liter vessel, vessel stand, valve and pipework.
Workheads
A variety of workheads and screens are available for Silverson’s small-scale In-Line mixers. These interchangeable workheads provide exceptional versatility, allowing each mixer to handle a wide range of tasks, such as emulsifying, homogenizing, disintegrating, dissolving, dispersing, blending, reducing particle size, and de-agglomerating. Changing from one head or screen to another is quick and simple, ensuring smooth transitions between mixing operations.
General Purpose Disintegrating Head
Used for a wide range of applications, this head will give the greatest throughput. Suitable for the blending of liquids of similar or greatly varying viscosities, its uses include the disintegration of solid and semi-solid materials.
Square Hole High Shear ScreenTM
The configuration and fine internal tolerances of this stator provide exceptionally high shear rates which are ideal for the rapid size reduction of soluble and insoluble granular solids. It is also suitable for the preparation of emulsions, gels and thickeners and fine collodial suspensions.
Slotted Disintegrating Head
For the disintegration of fibrous materials such as animal and vegetable tissue, as well as the disintegration and solubilization of “elastic” materials such as rubbers and polymers.
Emulsor Screens
These screens are suitable for liquid/liquid preparations and are especially useful for all emulsions. Emulsor screens are available in fine or medium perforations.
In-Line Multistage Workheads
Multistage workheads offer customizable mixing solutions through various combinations of inner and outer stators. By increasing the number of shearing actions per revolution of the rotor, these workheads deliver intensified mixing action, dramatically reducing processing times and enabling more products to be processed in a single pass.